Nowadays Modafinil 200mg became a popular medicine that is used for promoting wakfullness and cognitive performance of people. As a well-known nootropic, it is important to know the list of components present in Modafinil. In this post, we'll look at the essential components of Modafinil 200mg, and the role of each ingredien, mechanism of action and overall impact on cognitive performance.

List of Active and inactive compunds present in Modafinil:

Every pharmaceutical product contains both active and inactive compounds in it. Active compounds are meant to produce therapeutic effect or mediciial effect to treat the health issues in people. Whereas inactive compunds or additives are the ingredients that are meant to be mask the original drug flavor,to make the formulation, to hold the active compound, etc. 

Active compounds:

Modafinil: 

Modafinil is the Active pharmaceutical ingredient present in Modafinil 200mg tablets. Modafinil belongs to the eugeroics class of medicines, which enhance wakefulness. It is characterized chemically as a benzhydryl sulfinyl compound. Modafinil's chemical formula is C15H15NO2S, and its systematic name is 2-[(diphenylmethyl) sulfinyl]acetamide.

Action Mechanism:

The precise mechanism of action of modafinil is unknown. It is thought to interact with different neurotransmitters in the brain, including dopamine, norepinephrine, and histamine. The major target is assumed to be the dopamine transporter, which leads to increased levels of dopamine in specific areas of the brain, thus enhances wakefulness and alertness.

Inactive ingredients: 

As discussed earlier Modafinil 200mg tablets also contain inactive chemicals that contribute to the general composition, stability, and efficacy of the medicine. These inactive ingredients are important to the tablet's integrity, adequate absorption, and controlled release.

Microcrystalline cellulose:

Microcrystalline cellulose is used in pharmaceutical formulations as a binder and filler. It improves the cohesiveness of the tablet, helps in easy compression while manufacturing. 

Monohydrate Lactose:

Monohydrate Lactose is a commonly used as medicinal excipient. It acts as a filler, adds bulk to the tablet. It also helps to disintegrate th tablet after the adsorption. 

Pregelatinized Starch: 

Pregelatinized starch is a modified starch. It improves the stability of the tablet and disintegration properties of tablets. It ensures the adequate disintegration of the tablet in the digestive system and enhances adsorption. 

Sodium Croscarmellose:

Croscarmellose is a super-disintegrant that increases tablet breakdown in the gastrointestinal tract. This increases the release of modafinil in the body.

Povidone:

Povidone, commonly known as polyvinylpyrrolidone. It acts as a binding agent. It improves the cohesion of the tablet during production, helping to its structural integrity.

Magnesium Stearate (MS):

Magnesium stearate acts as a lubricant, preventing the ingredients from sticking to the manufacturing equipment. It helps to form the tablets smoothly and prevents caking.

Talc:

Talc is used in pharmaceutical formulations as an anti-adherent and glidant. It keeps tablet components from sticking to processing equipment and gives a smooth surface to the tablet.

Coating:

The outer coating of Modafinil 200mg tablets is essential for tablet protection, drug release control, and overall patient experience.

Hypromellose:

Hypromellose is a cellulose derivative that is widely used in medicinal coatings. It creates a protective layer around the tablet, preventing moisture from entering and assuring stability.

Titanium Dioxide (TiO2):

Titanium dioxide is a white pigment that adds color to tablet coatings. It also acts as an opacifier, improves the visual appearance of the tablet.

Polyethylene Glycol (Macrogol):

Macrogol is frequently used in tablet coatings due to its film-forming characteristics. It helps to give smoothness and glossiness to the tablet.

Conclusion:

Modafinil 200mg is a drug that is used to improve wakefulness and cognitive performance. Modafinil, the main active component, interacts with neurotransmitters to improve alertness. Furthermore, the inactive components and coating are important for stability, disintegration, and overall effectiveness of the tablet. 

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