G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder Background and Purpose Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self-medication and may be less dangerous than typical opioids because of the stronger preference of kratom alkaloids to induce receptor interaction with G proteins over β-arrestin proteins. The study hypothesizes that kratom (alkaloids) can also reduce alcohol intake. #science #research #kratomresearch #kratomstudy #alkaloids #proteins https://kratomlords.com/kratom-research/protein-biased-kratom-alkaloids-potential-treatments/